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Santa Cruz Biotechnology offers a variety of gene silencing products to target structural proteins via RNA interference (RNAi). Structural proteins are essential for maintaining the overall structural integrity of cells. Proteins which maintain structural integrity also ensure proper locomotion of the cell, which is essential for pinocytosis, phagocytosis and cytokinesis.

Cell structure influences cell surface adhesion and migration, both of which are important factors in cancer metastasis. In addition to cytoskeletal organization, structural proteins play a critical role in cell differentiation and tissue specialization. Structural proteins also play various roles in stabilizing actin filaments, thereby contributing to actin polymerization and reorganization. To knockdown expression of structural proteins, Santa Cruz Biotechnology offers siRNA, shRNA plasmid and shRNA lentiviral particles.